Tesamorelin is a synthetic 44-amino acid peptide analogue of Growth Hormone Releasing Factor (GHRF). It features a specialized N-terminal modification (trans-3-hexenoic acid) designed to enhance metabolic stability for prolonged observation in laboratory research settings.
Technical Profile
-
Molecular Weight: 5135.89 g/mol
-
Purity: ≥98% (HPLC)
-
Physical State: Lyophilized anhydrous solid
-
Solubility: Soluble in aqueous buffers or sterile deionized water
Research Focus
-
Receptor Affinity: Quantifying the binding kinetics of GHRF analogues to specific receptor sites in in vitro models.
-
Structural Stability: Examining the impact of N-terminal carbon chain modifications on peptide half-life.
-
Secondary Messenger Activation: Analyzing intracellular signaling cascades, specifically the modulation of cyclic adenosine monophosphate (cAMP) levels.
