HGH is a high-purity, recombinant DNA-derived polypeptide hormone consisting of 191 amino acids in a single-chain configuration. It is structurally identical to the 22 kDa isoform of endogenous somatotropin. In laboratory research, it is primarily used to study the complex endocrine signaling cascades that regulate metabolic rate, cellular proliferation, and the synthesis of secondary growth mediators.
Key Research Focus Areas:
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Somatotropic Signaling Pathways: Studied for its interaction with the GHR (Growth Hormone Receptor) and the subsequent activation of the JAK2/STAT5 signaling system.
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Secondary Mediator Induction: Investigated for its role in stimulating the hepatic synthesis and secretion of Insulin-like Growth Factor-1 (IGF-1) in vitro.
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Lipid and Carbohydrate Metabolism: Evaluated for its effects on lipolysis (breakdown of triglycerides) and its influence on glucose transport mechanisms in adipocytes and myocytes.
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Protein Synthesis Dynamics: Research focused on the peptide’s ability to promote nitrogen retention and accelerate amino acid transport for structural protein assembly.
Technical Details:
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Purity: 99%+ (verified via HPLC)
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Form: Lyophilized powder
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Vial Content: 10 IU | 12 IU | 36 IU (Approx. 3.33mg to 12mg per vial)
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Storage: Store at -20°C for long-term stability. Lyophilized vials are stable at room temperature for short durations during transit but must be refrigerated at 2–8°C upon arrival
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Reconstitution: Bacteriostatic water or Sterile Water for Injection.
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Molecular Weight: 22,124 Daltons (22 kDa)
Classification & Structure:
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Recombinant Somatropin: 191-amino acid single-chain polypeptide with two internal disulfide bridges
